abstract：Purpose:To identify the characteristics and initial disease severity of patients with nonalcoholic fatty liver disease (NAFLD) and assess incidence and risk factors for disease progression in a retrospective study. Methods:Patients ≥18 years of age without alcoholism or other liver diseases (eg, hepatitis B/C) were se...

journal_title：Clinical epidemiology

authors： Simeone JC,Bae JP,Hoogwerf BJ,Li Q,Haupt A,Ali AK,Boardman MK,Nordstrom BL

更新日期：2017-12-14 00:00:00

abstract：Background:The presence of comorbid medical conditions can significantly affect a cancer patient's treatment options, quality of life, and survival. However, these important data are often lacking from population-based cancer registries. Leveraging routine linkage to hospital discharge data, a comorbidity score was cal...

journal_title：Clinical epidemiology

authors： Lichtensztajn DY,Giddings BM,Morris CR,Parikh-Patel A,Kizer KW

更新日期：2017-11-20 00:00:00

abstract：Background:Hydroxychloroquine and chloroquine may reduce the risk of cancer as they inhibit autophagy, in particular, in people with connective tissue diseases. Methods:The hazard ratios of cancers, metastases, and death were assessed in adults with connective tissue diseases prescribed hydroxychloroquine/chloroquine ...

journal_title：Clinical epidemiology

authors： Fardet L,Nazareth I,Petersen I

更新日期：2017-11-03 00:00:00

abstract：OBJECTIVE:In medicine, many more prediction models have been developed than are implemented or used in clinical practice. These models cannot be recommended for clinical use before external validity is established. Though various models to predict mortality in dialysis patients have been published, very few have been v...

journal_title：Clinical epidemiology

authors： Ramspek CL,Voskamp PW,van Ittersum FJ,Krediet RT,Dekker FW,van Diepen M

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Validation of definitions used to identify conditions of interest is imperative to epidemiologic studies based on routinely collected data. The objective of the study was thus to estimate positive predictive values (PPVs) of International Classification of Diseases, 10th Revision (ICD-10) codes to identify c...

journal_title：Clinical epidemiology

authors： Munch T,Christensen LB,Adelborg K,Tell GS,Apalset EM,Westerlund A,Lagerros YT,Kahlert J,Xue F,Ehrenstein V

更新日期：2017-08-17 00:00:00

abstract：OBJECTIVE:The Department of Hematology, Zealand University Hospital, Denmark, and the National Institute of Public Health, University of Southern Denmark, created the first nationwide, population-based, and the most comprehensive cross-sectional health-related quality of life (HRQoL) survey of patients with myeloprolif...

journal_title：Clinical epidemiology

authors： Brochmann N,Flachs EM,Christensen AI,Andersen CL,Juel K,Hasselbalch HC,Zwisler AD

更新日期：2017-03-02 00:00:00

abstract：AIM OF DATABASE:The aim of the Danish Anaesthesia Database (DAD) is the nationwide collection of data on all patients undergoing anesthesia. Collected data are used for quality assurance, quality development, and serve as a basis for research projects. STUDY POPULATION:The DAD was founded in 2004 as a part of Danish C...

journal_title：Clinical epidemiology

authors： Antonsen K,Rosenstock CV,Lundstrøm LH

更新日期：2016-10-25 00:00:00

abstract：AIM OF THE DATABASE:The main purpose of the database of the Danish Renal Cancer Group (DaRenCaData) is to improve the quality of renal cancer treatment in Denmark and secondarily to conduct observational research. STUDY POPULATION:DaRenCaData includes all Danish patients with a first-time diagnosis of renal cancer in ...

journal_title：Clinical epidemiology

authors： Petersen AC,Søgaard M,Mehnert F,Larsen EH,Donskov F,Azawi NH,Kromann-Andersen B

更新日期：2016-10-25 00:00:00

abstract：AIM OF DATABASE:The aim of the Danish Heart Failure Registry (DHFR) is to monitor and improve the care of patients with incident heart failure (HF) in Denmark. STUDY POPULATION:The DHFR includes inpatients and outpatients (≥18 years) with incident HF. Reporting to the DHFR is mandatory for the Danish hospital departme...

journal_title：Clinical epidemiology

authors： Schjødt I,Nakano A,Egstrup K,Cerqueira C

更新日期：2016-10-25 00:00:00

abstract：AIM:In 2008, the Danish National Chronic Lymphocytic Leukemia Registry was founded within the Danish National Hematology Database. The primary aim of the registry is to assure quality of diagnosis and care of patients with chronic lymphocytic leukemia (CLL) in Denmark. Secondarily, to evaluate adherence to national gui...

journal_title：Clinical epidemiology

authors： da Cunha-Bang C,Geisler CH,Enggaard L,Poulsen CB,de Nully Brown P,Frederiksen H,Bergmann OJ,Pulczynski EJ,Pedersen RS,Nielsen LH,Christiansen I,Niemann CU

更新日期：2016-10-25 00:00:00

abstract：AIM OF DATABASE:The Danish Nonmelanoma Skin Cancer Dermatology Database was established in 2008. The aim of this database was to collect data on nonmelanoma skin cancer (NMSC) treatment and improve its treatment in Denmark. NMSC is the most common malignancy in the western countries and represents a significant challen...

journal_title：Clinical epidemiology

authors： Lamberg AL,Sølvsten H,Lei U,Vinding GR,Stender IM,Jemec GB,Vestergaard T,Thormann H,Hædersdal M,Dam TN,Olesen AB

更新日期：2016-10-25 00:00:00

abstract：AIM OF DATABASE:The aim of the National Database of Geriatrics is to monitor the quality of interdisciplinary diagnostics and treatment of patients admitted to a geriatric hospital unit. STUDY POPULATION:The database population consists of patients who were admitted to a geriatric hospital unit. Geriatric patients can...

journal_title：Clinical epidemiology

authors： Kannegaard PN,Vinding KL,Hare-Bruun H

更新日期：2016-10-25 00:00:00

abstract：:Routinely-collected health data (RCD) are now used for a wide range of studies, including observational studies, comparative effectiveness research, diagnostics, studies of adverse effects, and predictive analytics. At the same time, limitations inherent in using data collected without specific a priori research quest...

journal_title：Clinical epidemiology

authors： Nicholls SG,Langan SM,Sørensen HT,Petersen I,Benchimol EI

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:Assessment of psychosocial functioning in people with schizophrenia is important. The Global Assessment of Functioning (GAF-F) scale represents a widely applied, easy, and quick tool, but its validity and reliability have been debated. The aim was to investigate whether GAF-F scores are associated with other...

journal_title：Clinical epidemiology

authors： Köhler O,Horsdal HT,Baandrup L,Mors O,Gasse C

更新日期：2016-09-02 00:00:00

abstract：BACKGROUND:Data from the Nordic health care registers have been of great value in perinatal epidemiological research. It has been assumed that findings from the Nordic population (Denmark, Finland, Iceland, Norway, and Sweden) are applicable to other populations as well, including the population of the US. OBJECTIVE:T...

journal_title：Clinical epidemiology

authors： Löfling L,Bröms G,Bahmanyar S,Kieler H

更新日期：2016-08-03 00:00:00

abstract：INTRODUCTION:Smoking is a main risk factor for morbidity and mortality in people living with human immunodeficiency virus (PLHIV), but its potential association with renal impairment remains to be established. METHODS:We did a nationwide population-based cohort study in Danish PLHIV to evaluate the association between...

journal_title：Clinical epidemiology

authors： Ahlström MG,Feldt-Rasmussen B,Legarth R,Kronborg G,Pedersen C,Larsen CS,Gerstoft J,Obel N

更新日期：2015-08-28 00:00:00

abstract：BACKGROUND:Large-scale clinical registries are increasingly recognized as important resources for quality assurance and research to inform clinical decision-making and health policy. We established a clinical registry (SpineData) in a conservative care setting where more than 10,000 new cases of spinal pain are assesse...

journal_title：Clinical epidemiology

authors： Kent P,Kongsted A,Jensen TS,Albert HB,Schiøttz-Christensen B,Manniche C

更新日期：2015-08-13 00:00:00

abstract：BACKGROUND:A number of population-based studies have demonstrated lower cancer survival in elderly patients than among middle-aged or younger patients. Also, data quality in cancer registries has been shown to be associated with age. The objective of this study was to examine the recent age-specific cancer survival tre...

journal_title：Clinical epidemiology

authors： Innos K,Lang K,Pärna K,Aareleid T

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:National prescription databases are important tools in pharmacoepidemiological studies investigating potential long-term adverse events after drug use. Palivizumab is a biological pharmaceutical used as passive prophylaxis against severe infection with respiratory syncytial virus in high-risk children. OBJE...

journal_title：Clinical epidemiology

authors： Haerskjold A,Henriksen L,Way S,Malham M,Hallas J,Pedersen L,Stensballe LG

更新日期：2015-05-08 00:00:00

abstract：BACKGROUND:With the emergence of new lipid-lowering therapies, more patients are expected to achieve substantial lowering of low-density lipoprotein cholesterol (LDL-C). However, there are limited data examining the clinical experience of patients with low (<1.3 mmol/L) or very low (<0.65 mmol/L) levels of LDL-C. To pr...

journal_title：Clinical epidemiology

authors： Schmidt SA,Heide-Jørgensen U,Manthripragada AD,Ehrenstein V

更新日期：2015-02-26 00:00:00

abstract：PURPOSE:Rotavirus (RV) is a leading cause of severe gastroenteritis (GE) in children across the world. As there is a lack of epidemiological data for RV gastroenteritis (RVGE) in Saudi Arabia, this hospital-based study was designed to estimate the disease burden of RVGE and assess the prevalent RV types in Saudi childr...

journal_title：Clinical epidemiology

authors： Khalil M,Azhar E,Kao M,Al-Kaiedi N,Alhani H,Al Olayan I,Pawinski R,Gopala K,Kandeil W,Anis S,Van Doorn LJ,DeAntonio R

更新日期：2015-02-11 00:00:00

abstract：:The management of brain-dead organ donors is complex. The use of inotropic agents and replacement of depleted hormones (hormonal replacement therapy) is crucial for successful multiple organ procurement, yet the optimal hormonal replacement has not been identified, and the statistical adjustment to determine the best ...

journal_title：Clinical epidemiology

authors： Mi Z,Novitzky D,Collins JF,Cooper DK

更新日期：2014-12-22 00:00:00

abstract：BACKGROUND:Severe infection resulting in sepsis is recognized as a leading cause of morbidity and mortality worldwide. The purpose of this study is to use longitudinal, population-based data to report national-level hospital metrics, providing a current assessment of the status of sepsis hospitalizations in Canadian ch...

journal_title：Clinical epidemiology

authors： Thompson GC,Kissoon N

更新日期：2014-12-05 00:00:00

abstract：BACKGROUND:Long-term mortality and causes of death in patients with pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) are poorly documented. In this study, long-term mortality and causes of death in PTB and EPTB patients were compared with the background population and it was investigated whether mort...

journal_title：Clinical epidemiology

authors： Christensen AS,Roed C,Andersen PH,Andersen AB,Obel N

更新日期：2014-11-13 00:00:00

abstract：BACKGROUND:The study objective was to compare the Newcastle-Ottawa Scale (NOS) and the RTI item bank (RTI-IB) and estimate interrater agreement using the RTI-IB within a systematic review on the cardiovascular safety of glucose-lowering drugs. METHODS:We tailored both tools and added four questions to the RTI-IB. Two ...

journal_title：Clinical epidemiology

authors： Margulis AV,Pladevall M,Riera-Guardia N,Varas-Lorenzo C,Hazell L,Berkman ND,Viswanathan M,Perez-Gutthann S

更新日期：2014-10-10 00:00:00

abstract：:Sjögren's syndrome is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands. It can present as an entity by itself, primary Sjögren's syndrome (pSS), or in addition to another autoimmune disease, secondary Sjögren's syndrome (sSS). pSS has a strong female propensity and is ...

journal_title：Clinical epidemiology

authors： Patel R,Shahane A

更新日期：2014-07-30 00:00:00

abstract：PURPOSE:The primary objective of this study is to examine the race-specific associations between statin use and overall mortality, as well as cardiovascular and cancer mortality, among blacks and whites in the Southeastern United States (US). Little is known about these associations in blacks. PATIENTS AND METHODS:The...

journal_title：Clinical epidemiology

authors： Lipworth L,Fazio S,Kabagambe EK,Munro HM,Nwazue VC,Tarone RE,McLaughlin JK,Blot WJ,Sampson UK

更新日期：2013-12-19 00:00:00

abstract：PURPOSE:Lifestyle factors may influence observed associations between proton pump inhibitor (PPI) usage and health outcomes. The aim of the study reported here was to examine characteristics and differences in lifestyle among PPI users and nonusers. METHODS:This cross-sectional study utilized data from a 2006 populati...

journal_title：Clinical epidemiology

authors： Hvid-Jensen F,Nielsen RB,Pedersen L,Funch-Jensen P,Drewes AM,Larsen FB,Thomsen RW

更新日期：2013-12-04 00:00:00

abstract：BACKGROUND:A number of studies have shown poorer survival among cancer patients with comorbidity. Several mechanisms may underlie this finding. In this review we summarize the current literature on the association between patient comorbidity and cancer prognosis. Prognostic factors examined include tumor biology, diagn...

journal_title：Clinical epidemiology

authors： Søgaard M,Thomsen RW,Bossen KS,Sørensen HT,Nørgaard M

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The Danish National Registry of Patients (DNRP) is a potentially valuable resource for monitoring national trends in the use of chemotherapy and evaluating the benefits and harms of alternative treatments among colorectal cancer (CRC) patients in Denmark. However, the validity of chemotherapy reporting in th...

journal_title：Clinical epidemiology

authors： Lund JL,Frøslev T,Deleuran T,Erichsen R,Nilsson T,Pedersen AN,Høyer M

更新日期：2013-08-30 00:00:00

abstract：OBJECTIVE:We examined the association between lifestyle factors and menstrual cycle characteristics among nulliparous Danish women aged 18-40 years who were participating in an Internet-based prospective cohort study of pregnancy planners. METHODS:We used cross-sectional data collected at baseline to assess the associ...

journal_title：Clinical epidemiology

authors： Hahn KA,Wise LA,Riis AH,Mikkelsen EM,Rothman KJ,Banholzer K,Hatch EE

更新日期：2013-08-19 00:00:00

abstract：:Memory diseases are the most important determinant of health care service use and quality of life among older individuals. Adverse effects of medication are common among older people, but this age group is underrepresented in clinical trials. Finnish statutory health care and prescription registers, together with pers...

journal_title：Clinical epidemiology

authors： Tolppanen AM,Taipale H,Koponen M,Lavikainen P,Tanskanen A,Tiihonen J,Hartikainen S

更新日期：2013-08-07 00:00:00

abstract：BACKGROUND:Osteonecrosis of the jaw (ONJ) is an adverse effect of drugs that suppress bone turnover - for example, drugs used for the treatment of postmenopausal osteoporosis. The Danish National Registry of Patients (DNRP) is potentially valuable for monitoring ONJ and its prognosis; however, no specific code for ONJ ...

journal_title：Clinical epidemiology

authors： Gammelager H,Sværke C,Noerholt SE,Neumann-Jensen B,Xue F,Critchlow C,Bergdahl J,Lagerros YT,Kieler H,Tell GS,Ehrenstein V

更新日期：2013-08-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the most important causes of nosocomial infections worldwide. Since the global spread of MRSA in the 1960s, MRSA strains have evolved with increased pathogenic potential. Notably, some strains are now capable of causing persistent infections not only in...

journal_title：Clinical epidemiology

authors： Chatterjee SS,Otto M

更新日期：2013-07-04 00:00:00

abstract：BACKGROUND:The aim of the present study was to validate the data in the Aarhus Sarcoma Registry (ASR), to determine if this registry is population-based for western Denmark, and to examine the incidence of sarcomas using validated, population-based registry data. METHODS:This study was based on patients with bone and ...

journal_title：Clinical epidemiology

authors： Maretty-Nielsen K,Aggerholm-Pedersen N,Keller J,Safwat A,Baerentzen S,Pedersen AB

更新日期：2013-03-06 00:00:00

abstract：PURPOSE:Large-scale observational studies based on existing medical databases may have an important role in studies of long-term effects of different treatments in prostate cancer patients if the coding of the treatment is valid. We therefore estimated the positive predictive value (PPV) and negative predictive value (...

journal_title：Clinical epidemiology

authors： Jespersen CG,Borre M,Nørgaard M

更新日期：2012-01-01 00:00:00

abstract：:The Danish health care system provides partial reimbursement of most prescription medications in Denmark. The dispensation of prescription medications is registered in administrative databases. Each time a prescription is redeemed at a pharmacy, an electronic record is generated with information related to the user, p...

journal_title：Clinical epidemiology

authors： Johannesdottir SA,Horváth-Puhó E,Ehrenstein V,Schmidt M,Pedersen L,Sørensen HT

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Although hypertrophic scar (HTS) formation following cleft lip repair is relatively common, published rates vary widely, from 1% to nearly 50%. The risk factors associated with HTS formation in cleft patients are not well characterized. The primary aim of this retrospective study of 180 cleft lip repairs is ...

journal_title：Clinical epidemiology

authors： Soltani AM,Francis CS,Motamed A,Karatsonyi AL,Hammoudeh JA,Sanchez-Lara PA,Reinisch JF,Urata MM

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Few modern population-based estimates of the prognosis of ruptured abdominal aortic aneurysm (rAAA) exist. METHODS AND MATERIALS:From 1994-2008, a total of 6954 rAAA cases were identified in Danish nationwide population-based registries. RESULTS:Of 3148 (45%) surgery cases, 1454 (46%) died within 30 days...

journal_title：Clinical epidemiology

authors： Lindholt JS,Søgaard R,Laustsen J

更新日期：2012-01-01 00:00:00

abstract：:Long-term storage of biological samples from patients has become increasingly important in studies of disease control and treatment. The first nationwide Danish diabetes project, ie, The Danish Center for Strategic Research in Type II Diabetes (DD2), aims to improve treatment and the long-term outcome of patients with...

journal_title：Clinical epidemiology

authors： Christensen H,Nielsen JS,Sørensen KM,Melbye M,Brandslund I

更新日期：2012-01-01 00:00:00